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CASE REPORT 

Cutaneous Metastatic Renal Cell Carcinoma to the Skin Presenting as a Zosteriform Eruption

Hari Menon, Richard Bernert, Kimberly Jared, Burrell Wolk and Neil F Fernandes

Abstract

Cutaneous metastasis of internal malignancy is an uncommon but not rare phenomenon. Renal cell carcinoma is a visceral malignancy that rarely metastasizes to the skin and typically presents as a solitary red, purple nodule when it does. We describe a case of metastatic renal cell carcinoma to the skin presenting as a zosteriform eruption.

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Short Commentary 

Quality of Life in Women with Alopecia

Danyelle Dawes

Abstract

Hair loss is a psychologically devastating disorder, causing grave distress to patients of all ages, genders, and nationalities. Due to the visible nature of hair loss, individuals become increasingly self-conscious, and over time may develop anxiety or depression. Furthermore, the psychological stress related to alopecia can impair functioning in social and professional arenas, affecting relationships and creating work related problems.

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Case Report 

Excellent Response to Hydroxychloroquine in a Young Man with Lupus Erythematosus Panniculitis

Anibal Maria Parigini, Maria Clara de Diego, Julieta Ruiz Beguerie, Victoria Duran Paredes and Javier Anaya

Abstract

Lupus erythematosus panniculitis is a rare variant of lupus erythematosus. We present the case of a young man with ulcerative colitis treated with mesalazine and a history of recurrent painful and indurated lesions on his face. A diagnosis of lupus profundus was made taking in account the clinical manifestations and the histological and immunofluorescence findings. An excellent initial response and stabilization of the dermatosis was achieved with a combined treatment with antimalarial drugs and systemic corticosteroids.

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Case Report 

Chronic Papillomatous Dermatitis in a Patient with a Urinary Ileal Diversion: A Case Report and Review of the Literature

Pooja H Rambhia, Ruzica Z Conic, Kord Honda and Danyelle Dawes

Abstract

Gastrointestinal surgical procedures result in approximately 100,000 ostomies per year in the United States, with over 10,00,000 people living with intestinal stomas.

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Research Article 

Descriptives Module - The Power of the Student Educator

Maria McGowan, Hannah Hill, Janiene D Luke and Sharon E Jacob

Abstract

Dermatology education is faced with the challenge of developing curricula for learners who possess a wide range of learning styles, strengths, and life experiences. Utilization of the V.A.R.K (Visual, Aural, Reading/Writing, Kinesthetic) model of learning, outcome-based adult-learning theory, and inclusive participatory teaching offers a unique opportunity to teach dermatology.

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Case Report 

Multimodal Therapy for Recalcitrant Cutaneous Fusarium Solani Infection in a Patient with Hyper-IgE Syndrome

Matthew D Belcher, Lisa Ishii and Jake E Turrentine

Abstract

Hyper IgE Syndrome (HIES) is an inherited immunodeficiency syndrome with an increased susceptibility to cutaneous fungal infections. While systemic antifungals are often the therapy of choice, many non-pharmacologic treatment options have been shown to improve clearance of these infections.

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Review Article 

Skin Immunodysregulation Disorders - The T-Cell Mediated Dermatoses

Margit LW Juhasz and Sharon E Jacob

Abstract

The skin harbors an immune organ, made up of keratinocytes, dendritic cells (also known as Langerhans cells), as well as immune-derived nomadic cells (e.g. lymphocytes, neutrophils and eosinophils), which can respond to a variety of insults including inflammation, wound repair and infection.

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Research Article 

Syndecan 1: A Useful Marker for Differential Diagnosis in Pseudocarcinomatous Hyperplasia and Squamous Cell Carcinoma

Mariana Catalina De Anda Juarez, Ramon Felipe Fernandez Martinez, Maria Elisa Vega, Ronell Bologna Molina and Gabriela Moreno Coutino

Abstract

Some proteins have been used as immunohistochemical markers for tumor diagnosis. Such is the case of syndecan-1, one of the four transmembrane heparin sulfate proteoglycans which are mainly present on the cellular surface.

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Case Report 

Multiple Myeloma with Skin and Breast Involvement: A Case Report

Suzan Demir Pektas, Gokhan Pektas, Ceyda Tetik, Tuba Edgunlu, Havva Solak Ozseker, Yelda Dere and Gursoy Dogan

Abstract

Multiple myeloma; that constitutes 10% of all hematologic malignancies and approximately 1% of whole cancers, is a plasma cell dyscrasia. Extramedullary involvement is often seen in the upper skeletal system, besides it can be seen on the skin and breast, rarely.

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Case Report 

Infantile Haemangioma: Treatment in a Preterm Infant

Ximena Rodriguez-Vasquez, Elena Naz-Villalba, Marta Elosua-Gonzalez, Elena Garcia-Zamora, Ana Martin-de-Rosales and Jose-Luis Lopez-Estebaranz

Abstract

Infantile Haemangioma (IH) is the most frequent benign vascular tumor of infancy, and active treatment is indicated in special situations. Topical timolol, it has been reported to be an effective and safe treatment for superficial IH, with rare adverse effects.

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Research Article 

Prevalence of Depression in Mexican Patients with Pemphigus Vulgaris: An Observational Study

Andres Tirado-Sanchez, Alexandro Bonifaz, Isabela Perez-Prieto and Rafael Reyes-Vazquez

Abstract

Pemphigus vulgaris is an autoimmune bullous disease mediated mainly by IgG autoantibodies directed to desmosome proteins. The mental health of these patients has not been extensively described in previous studies.

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CASE REPORT 

The Mortal Association of Rothmund Thomson Syndrome and H1N1

Kocak Abdullah Osman , Bayramoglu Atif and Calbay Ayca

Abstract

Rothmund Thomson Syndrome (RTS) is a rare autosomal recessive disorder. It was first described in 1868 by a German ophthalmologist named August Rothmund as a syndrome consisting of bilateral juvenile cataract sand rash.

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CASE REPORT 

Tinea Pedis/Gram-Negative Toe Web Infection Treated with a Dilute Povidone-Iodine and Dimethylsulfoxide Preparation

Kara Capriotti, Kevin Stewart, Jesse Pelletier and Joseph Capriotti

Abstract

Interdigital toe web infection is most frequently a polymicrobial complex disease process being caused by fungal, yeast or bacterial etiological factors, with a wide range of clinical manifestations. Treatment can prove to be difficult if the mixed etiology is not readily identified and furthermore more than one prescription is often required for eradication.

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COMMENTARY 

Aging Kinetics of Human Hearts and Skin: New Aging Theories and Implications in the Use of Sunscreens

Win L Chiou

Abstract

Published data on cardiac indexes and superficial nutritive capillary densities from photo-protected and photo-exposed areas as well as collagen contents of skin of forearms from a large number of normal subjects over several decades of lifespan were reanalyzed using a first-order kinetic model. Excellent logarithmic linear fittings were all obtained. Slopes from the photo-protected and photo-exposed studies were virtually parallel.

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