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Research Article 

Sport as a Treatment Aimed to the Recovery in Severe Psychiatric Disorders: Health, Functioning and Adjustment

Giorgio Corretti, Roberta Guerra, Christian Martini, Fabrizio Lazzerini and Alfredo Sbrana

Abstract

According to the Council of Europe, Sport could be defined as "all forms of physical activity which, through casual or organized participation, aim at expressing or improving physical fitness and mental well-being, forming social relationships or obtaining results in competition at all levels" (752 Meeting of the Ministers' Deputies - Meetings 2002 - 2001/16 May 2001).

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Research Article 

Phenytoin in Bipolar Depression: An Old Chapter, but Not Yet Properly Evaluated

Jan M Keppel Hesselink and Stephen M Stahl

Abstract

To review and analyze the repurposing of phenytoin as a treatment for bipolar disorders. Phenytoin is an 80-years-old drug and its putative clinical value is neglected for psychiatric disorders. Only few studies have been published in this field, and most studies are pilot trials. However, since the beginning of the use of phenytoin in the neurological clinic, a number of observations suggests its clinical relevance in a variety of indications, related to depression, anxiety and psychosis. As the pharmacotherapeutic arsenal for bipolar disorders is still suboptimal, we will discuss in this article the data related to the potential value of phenytoin in the treatment of bipolar disorders.

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Short Communication 

An Assessment of Zebrafish Natural Color Preference and its Modification by Stimuli

Dawn Salmon and Mohammad Kutub Ali

Abstract

Zebrafish have been known to show color preference. Conditions that enhance or diminish color preferences are largely inconclusive. In this study, we used the T-Maze with red and green arms to test the Zebrafish color preference.

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Research Article 

Depression and Anxiety during Pregnancy: The Influence of Maternal Characteristics

Kim FE van de Loo , Richelle Vlenterie, Sylke J Nikkels, Peter JFM Merkus, Jolt Roukema, Chris M Verhaak, Nel Roeleveld and Marleen MHJ van Gelder

Abstract

Depression and anxiety during pregnancy are associated with adverse health outcomes for both mother and child. This study aimed to investigate the occurrence of symptoms of depression and anxiety in early and late pregnancy, the longitudinal changes from early to late pregnancy.

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