Home / Browse Journals & Books / Chromatography and Spectroscopy Techniques / Archive
Research Article Volume 2 Issue 1
Abstract: The aim of this study was to investigate the effect of UV irradiation on streptozotocin-induced diabetic skin. 42 hairless
male mice were divided into three groups of control non-diabetic and with dose of streptozotocin 20 and 30 mg/kg. Both
FT-IR and Raman spectra showed considerable changes between the diabetic and non-diabetic mice, as well as after
irradiation. The most important changes between healthy and diabetic groups were observed in the reduction
| | |
Abstract: Ketoconazole is the active ingredient in an antifungal liquid formulation for topical application. A binary gradient HPLC analysis indicated that ketoconazole in the formulation produced four degradation products at minor levels after storage at room temperature for about 3 years. These degradation products were isolated and purified using semi-preparative HPLC procedures followed by analysis using off-line HPLC-ESI-MS and HPLC-ESI-MS/MS.
Research Article Volume 1 Issue 1
Abstract: Monitoring of trace organic contaminants in aquatic media has become a major concern today. The presence of Carbamazepine (CBZ), anticonvulsant and analgesic used in the treatment of pain associated with trigeminal neuralgia, has been reported in effluents from sewage treatment plants due to its low biodegradability.
Editorial Volume 1 Issue 1
Abstract: The results obtained during the study of mutations on the gene coding for the human prion protein showed that the only major consequence of mutations is the perturbation of the protein surface electrostatic potential which subsequently is responsible for the convergence of PrPc to PrPsc.