Journal of Neurodegenerative Disorders

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Orginal Research 

Near Infrared Spectroscopy alike Magnetic Resonance Imaging: Complementary Data in Rat Brain after Cocaine Treatment

Francesco Crespi, Francesca Formenti and Francesco Congestri

Abstract

Magnetic Resonance Imaging (MRI) and Near Infrared Spectroscopy (NIRS) are two major in vivo non invasive methodologies more and more applied in research. The first more than the second is largely used also in clinical domain. Both techniques are more or less related to the effectiveness of oxygen levels and/or functionality in blood.

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Case Report 

The Dilemma of Raised Blood Levels of Folate and B12 in Autism

D Lonsdale

Abstract

It has recently been reported that a raised level of folate and/or vitamin B12 in the blood of a newly parturient woman forecasts a marked increase in the possibility that the newborn infant will later develop autisma. The text that follows refers to the cases of two boys, each of which had suffered repeated episodes of acute febrile cervical lymphadenopathy.

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Original Article 

Salvia Hispanica L (Chia Seeds) as Brain Superfood-How Seeds Increase Intelligence

Peter Onneken

Abstract

The influence of nutrition on cognitive abilities is undisputed in academic literature. Numerous studies have shown that the effects of polyunsaturated fats and other foods, such as milk, meat or oils are in fact measurable.

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Research Article 

Translational NIRS: Parallel Alteration of Brain Metabolism Following Alcohol Intake in Rodents and Man

Francesco Crespi, Francesco Congestri and Maurizio Donini

Abstract

Near-infrared spectroscopy (NIRS) provides a non-invasive, non-ionizing means to monitor total haemoglobin concentration and oxygen saturation in the living tissue allowing monitoring oxygen sufficiency. Main applications of NIRS are in the study of the transport of the oxygen to the muscles, the cellular metabolism and the cerebral haemodynamics. Fewer NIRS studies have been performed at the Central Nervous System (CNS), mainly to monitor oxygen sufficiency, brain functions and diseases.

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Case Report 

Cerebrotendinous Xanthomatosis: Literally an Orphan Disease in Brazil: Case Report

Emanuelle Bianchi da Silva, Brenda Camila Reck de Oliveira, Taline Alisson Artemis Lazzarin Silva, Letícia da Silva Schran and Paulo Eduardo Mestrinelli Carrilho

Abstract

Cerebrotendinous Xanthomatosis (CX) is an exceedingly rare autosomal recessive lipid storage disorder due to homozygous mutation of the mitochondrial enzyme sterol 27-hydroxylase.

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Case Report 

Caregiver Syndrome

Neslihan Lok and Kerime Bademli

Abstract

Caregiver syndrome is caused by continuous care without interrupting a chronic patient. The physical, emotional and economic difficulties experienced by caregivers, the losses in the functioning of the patient, and the absence of the caregiver's free time, negatively affect the quality life of caregivers.

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short communication 

Effects of Surface Tissue Compression on Muscle Tone of Stroke Patients

Crislaine de Lima, Vanessa de Fatima Dias, Gabriel Padua da Silva, Evandro Marianetti Fioco, Camila Roza Goncalves, Oswaldo Stamato Taube, Saulo Fabrin, Simone Cecilio Hallak Regalo and Edson Donizetti Verri

Abstract

There are two types of cerebrovascular accident, or stroke. An ischemic stroke is caused by a blockage of blood flow, and a hemorrhagic stroke is caused by a breakage in a blood vessel.

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Research Article 

Evaluation of the Elderly Living in the Central Kirşehir Using Standardized Mini-Mental State Examination

Gokce Demir, Ayla Unsal, Safak Taktak and Sevil Bicer

Abstract

In the last century technological developments contribute positively to the living conditions, quality improvement in health care, higher levels of education, advances in public health and preventive medicine are the positive society of the effects of, has led to the extension of the average life expectancy.

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Research Article 

Lessons from the Discovery of the "Calcium Paradox" due to Ca2+/Camp Interaction

Leandro Bueno Bergantin and Afonso Caricati-Neto

Abstract

The notion of stimulus-secretion initially resulted from the experiments performed by Douglas and Rubin in the sixties. Using adrenal chromaffin cells, Baker and Knight revealed in seventies that a rise in the cytosolic Ca2+ concentration ([Ca2+]c), is an elementary requirement to trigger transmitter release.

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