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Mini Review Pages 72-73
Abstract: Topical use is the main advantage for dermatological therapy due to the outer-layer features of skin. Consequently, numerous preparations are available for the dermatosis. However, the efficacy evaluation of different preparations accurately is always very difficult. Psoriasis is a common skin condition characterized by persistent erythematous scaly plaque. It is estimated about 3% population suffered from this notorious calcitrant disease.
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Case Report Pages 68-71
Abstract: Granuloma Annulare (GA) is a non-life threatening, granulomatous dermatosis of uncertain pathogenesis with a preference for females and mean onset after 50 years of age. Clinically, it typically appears as non-scaly, skin-colored or erythematous papules coalescing into an annular plaque. Lesions are most commonly localized in an acral distribution but can be generalized.
Case Report Pages 62-67
Abstract: The management of MF-CTCL is based on a "stage-based" approach and an evaluation by a multidisciplinary team is preferred. Initial treatment in patients with local (patch/plaque) disease includes skin-directed therapies (localized or generalized), with the addition of systemic biologic therapy for refractory, or progressive disease. In patients with unfavorable prognostic features (e.g., folliculotropic or large-cell transformed MF, or B1 involvement) systemic biologic therapies may be introduced earlier in the treatment algorithm. Patients who do not respond to biologic therapy or those with very aggressive or extracutaneous disease may be treated with chemotherapy.
CASE REPORT Pages 58-61
Abstract: Cutaneous metastasis of internal malignancy is an uncommon but not rare phenomenon. Renal cell carcinoma is a visceral malignancy that rarely metastasizes to the skin and typically presents as a solitary red, purple nodule when it does. We describe a case of metastatic renal cell carcinoma to the skin presenting as a zosteriform eruption.
Short Commentary Pages 55-57
Abstract: Hair loss is a psychologically devastating disorder, causing grave distress to patients of all ages, genders, and nationalities. Due to the visible nature of hair loss, individuals become increasingly self-conscious, and over time may develop anxiety or depression. Furthermore, the psychological stress related to alopecia can impair functioning in social and professional arenas, affecting relationships and creating work related problems.
Case Report Pages 51-54
Abstract: Lupus erythematosus panniculitis is a rare variant of lupus erythematosus. We present the case of a young man with ulcerative colitis treated with mesalazine and a history of recurrent painful and indurated lesions on his face. A diagnosis of lupus profundus was made taking in account the clinical manifestations and the histological and immunofluorescence findings. An excellent initial response and stabilization of the dermatosis was achieved with a combined treatment with antimalarial drugs and systemic corticosteroids.